ER 200 mg low, dosage)
The appearance of abnormal neurologic signs and symptoms demands the prompt evaluation of the benefit/risk ratio of the continuation of therapy (see adverse reactions ). Although the pigment which is probably responsible for this phenomenon has not been positively identified, it is almost certainly a metabolite of metronidazole and seems to have no clinical significance. In these multicenter clinical trials, there were no statistically significant differences in the incidence rates of yeast vaginitis for groups of patients treated with flagyl ER or the vaginal comparator. Neurotoxic effects, including seizures and peripheral neuropathy, have been reported after 5 to 7 days of doses of 6 g.4 g every other day. Use in Patients with Blood Dyscrasias Metronidazole is a nitroimidazole and should be used with caution in patients with evidence of or history of blood dyscrasia.
ER 750 mg daily MeanSD (N24)
There were no significant changes in the AUC24 of hydroxyl-metronidazole in these hepatically impaired patients. Clinical pharmacology, Absorption ). From Infectious Disease Resources Featured Centers Health Solutions From Our Sponsors Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA.
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Interaction with Alcohol Use of oral metronidazole is associated with a disulfiram-like reaction to alcohol, including abdominal cramps, nausea, vomiting, headaches, and flushing. Find Lowest Prices on, flagyl ER (metronidazole) Extended-release Tablets, 750 mg, to reduce the development of drug-resistant bacteria and maintain the effectiveness of flagyl ER, and other antibacterial drugs, flagyl ER should be used only to treat or prevent infections. In geriatric patients, monitoring for metronidazole associated adverse events is recommended (see precautions ). This article explains in detail the factors that will affect your dose and also provides dosing guidelines for treating specific conditions.). Metabolism/Excretion The major route of elimination of metronidazole and its metabolites is via the urine (60 to 80 of the dose with fecal excretion accounting for 6 to 15 of the dose. Keep taking it even if you feel better in a few days.